Thyroid-Adrenal-Pancreas Axis
from Amandha D Vollmer’s Telegram channel
Healthy adrenal glands are required for the conversion of inactive T4 into active T3.
When the adrenals have reached a state of fatigue, they are no longer producing sufficient cortisol or DHEA. This leaves individuals more susceptible to chronic diseases from an inability to compensate for the stresses they encounter on a daily basis. It is very important to treat the adrenal glands before commencing treatment of the thyroid. Increasing thyroid hormone production while the adrenals are in fatigue can overwhelm the adrenals and lead to further exhaustion.
The inner medulla produces adrenalin and noradrenalin also known as norepinephrine and epinephrine. The cortex is under the control of hormones produced in the brain and the medulla is under the control of the nervous system. If the adrenal glands are fatigued and not ready for menopause, there will be an exaggeration of menopausal symptoms such as hot flashes, weight gain, sleep problems, bone loss, mood swings, depression, anxiety, loss of sex drive and vaginal dryness.
Aldosterone
Low salt diets and high water intake put a major stress on the adrenal glands to retain as much salt as possible as the blood becomes more diluted from the extra water intake. One of the easiest ways to maintain healthy adrenals is to consume a half- teaspoon of unrefined Celtic sea salt every morning with a few glasses of water.
Aldosterone Issues:
• Craving salt
• Fluid retention in the arms and legs
• Pupils do not stay constricted when exposed to light
• Rough or sandpaper tongue
• Excessive urination – up to 15-20 times/day
• Excessive sweating even without activity
Adrenaline
Adrenaline produced by the adrenal medulla will also raise blood sugar if there is stress on the body. Adrenaline will also increase fat circulation so that it can be burned as energy. This is not a good scenario for someone who is sitting at a desk and under major stress. Large amounts of fat and sugar floating in the bloodstream should be utilized to run from a lion which is our built-in survival mechanism. If there is no activity, the excess sugar will be converted into fat and stored mainly around the mid-section, hips and thighs.
The adrenal cortex communicates with the pituitary gland and hypothalamus in the brain. The hypothalamus reads the amount of circulating hormones and tells the pituitary to make hormones that directly tell the cortex to make hormones. This is called the HPA axis or hypothalamic-pituitary-adrenal axis.
All hormones are secreted on a circadian rhythm over a 24-hour period. Cortisol is especially representative of this rhythm as cortisol production is the highest in the early morning and then slowly tapers off as the day progresses. Cortisol levels are lowest at night so that the body can repair itself to the best of its ability. You lose two-thirds of your stored sugar while sleeping and cortisol production ensures balanced blood sugar during the night. If the adrenals are fatigued, you may have trouble staying asleep as the body will make adrenaline to raise blood sugar due to inadequate cortisol production which is enough to wake you up. If your adrenals are in overdrive with too much cortisol production, then you probably have trouble falling asleep. If you are a slow starter in the morning, your adrenals are probably fatigued and can’t make adequate cortisol to raise blood sugar and get you going in the morning.
Hypoglycemia
Hypoglycemia is a condition in which there is inadequate cortisol to raise blood sugar into the normal range. We usually see adrenal fatigue and hypoglycemia together. Hypoglycemics develop symptoms of low blood sugar and need to eat something to normalize blood sugar levels. They may feel shaky, irritable, light-headed, fatigued or may crave sugar because their adrenal glands cannot raise blood sugar into the normal range. Once hypoglycemics rejuvenate their adrenal glands, the symptoms will subside.
